Testing for environmental toxins has never been simpler!

With DBS, just a small prick of your finger is all it takes.

Just three steps to an answer:  Collect, Analyze and Report

You provide us with a drop of blood. We introduce a reagent with proven technology that helps us make a precise and accurate determination of the toxins or biomarkers present. The results from this analysis are sent to you and your doctor.

Three steps to perform QualeVita Tests using DBS or Dried Blood Spot sample collection - spot your blood and send in mail, QualeVita analyzes your blood, and returns a report

Our approach requires less blood and improves test accuracy

Our approach uses Dried Blood Spot (DBS) analysis with Direct Isotope Dilution Mass Spectrometry (D-IDMS) to get the accurate test results you need, with only a finger or heel prick required.  Only a drop of blood yields more accurate results at affordable prices.

Child Friendly

Only a finger or heel prick is required, reducing physical demands and emotional distress for children and adults.

Proven Accuracy

Isotope Dilution Mass Spectrometry is proven to measure low toxin concentrations with greater accuracy.

Superior Convenience

Provide a blood sample without a trip to the lab.  There are no appointments, travel, or lines.

Cost-Effective

Our tests reduce sample size, giving more information with less blood. Higher accuracy reduces retesting.

How do I use DBS to collect a sample?

shopping cart showing the order step

Order

Order individual test or a test panel through physician. A DBS card with test-specific isotope standards impregnated in it arrives at your home or at your doctor’s office.

image of hand showing sample collection step of making a finger prick to collect blood sample on DBS card for analysis

Collect

In the comfort of your own home or doctor’s office, simply prick finger or heel and place one drop of blood per spot on the DBS card. The DBS card requires 4 spots of blood.

Image of delivery van showing that the test results from your blood spots are returned to you

Return

Seal the enclosed bag and return the DBS card to QualeVita via post, ground, or overnight.  Once received, your card will be analyzed and the results returned to you and your physician.

The chain of custody is established when the envelope is sealed.

 

What is Dried Blood Spot Analysis?

Dried Blood Spot analysis (DBS) is a form of bio-sampling where blood samples, typically from a finger or heel stick, are blotted and dried on filter paper for shipment, analysis, and storage.

Dried blood spot analysis has many advantages over clinical blood draws including:

  • No need for cold storage
  • No phlebotomist required
  • Facilitates pediatric studies
Image of a DBS blood spot collection card showing four spots and a bar code for sample id

The Advantages of DBS vs. a Typical Blood Draw

Dried Blood Spot Clinical Blood Draw
0.045 cc required (15 ul/spot) 5 - 30 cc required (5,000 - 30,000 ul)
Finger/Heel Prick - no syringes Intravenous blood draw
Collect at home Appointment at a lab or clinic
Room Temperature Stability - seal and ship Special packaging / dry ice required
Not dangerous good - no special packaging Special handling / packaging required
Validated and approved Validated and approved

How Does Direct Isotope Dilution Mass Spectrometry Provide More Accurate Results?

Introduction

Direct Isotope Dilution Mass Spectrometry (D-IDMS) is a state-of-the-art analytical technique that dramatically increases the accuracy, precision, and reproducibility of analytical instrumentation used in clinical analysis, and has the unique ability to track and measure changes in samples from the moment of collection to the instant of analysis.

D-IDMS has been proven in the chemical, energy, and environmental fields for many years, however has only recently been applied to biological and clinical samples. It is regarded by the National Institute of Standards & Technology (NIST) as a “definitive method” because it is a method of proven high accuracy. The accuracy is afforded by adding a known amount of a non-radioactive or so-called “stable” chemical isotope to the sample.

Suppose a blood sample contains many things, including the elements zinc, (Zn) iron (Fe), and lead (Pb).  We want to know how much lead (Pb) is present, but how to you count all of the lead in the blood. To further confuse things, lead has four stable isotopes 204Pb, 206Pb, 207Pb and 208Pb. In nature, the abundance of these isotopic forms of lead are 1.4%, 24.1%, 22.1%, and 52.4% respectively.

How is direct isotope dilution mass spectrometry used to determine how much and which type of lead is in your blood?  A known quantity of our lead isotope is combined with the sample. We add some 207Pb and 208Pb in an exact ratio that we know. We can now analyze the total amount of lead, and the amount of each isotope. The addition of the isotope allows us to measure if there was a contamination, or in the case of biomarkers, a change in the sample from point of collection to point of analysis, by ensuring the proper amount and ratios are accounted for.

qualevita-idms-blood-drop-measurements

FIGURE 3.

In summary, direct Isotope dilution mass spectrometry spikes a stable isotope of the chemical whose concentration (amount) in the sample is unknown. By measuring the masses of the isotopes added and the total of the mass of the known spike and unknown sample using mass spectrometry, a ratio of the spiked isotope to the unknown and total amounts can be determined and a more accurate result reported.

FAQs

Do I need to go to a lab to give my blood for the test?
No. You can give a blood sample from a finger or heel prick in the comfort of your doctor’s office or home.
How does the sample get to the lab for analysis?

The DBS (Dried Blood Spot) card is sealed in an envelope and sent to the lab via mail or express. No special shipping requirements such as ice, hazardous material containers, or overnight express are required.

Do I need my doctor to order a QualeVita test?

Yes, currently your doctor orders QualeVita lab tests.

How many tests can you do using one spot of blood?

We can run two to four test panels per dried blood spot card. More than one drop of blood may be needed, but no more than a single finger or heel prick should be adequate.

What tests do you offer?

We offer a dedicated pregnancy panel for women who are or plan to become pregnant, an autism spectrum disorder panel that identifies the disease as it is attacking the immune system, and a series of multi element residue scans (MER) that can be ordered by your doctor for 50+ different metals and over 40 persistent organic pollutants (POPs).  Visit Our Tests for a summary of available tests.

Why is your test more accurate?

Our patented technology provides us the means to measure any analyte (chemical compound) in your original sample with unequalled degree of accuracy and precision. Our technology eliminates most errors associated with transportation, sampling, sampling, instrumentation and consistently produces accurate and precise results. This is particularly important for many analytes that are not stable and begin to change into other forms or degrade after they are collected. Our technology has the ability to account for those chemical changes and accurately measure concentration of the analytes of interest in the sample.

What information is included in a report?

The report will provide the concentration of the analytes in the blood sample along with the reference values within a range.  Laboratory test results are not meaningful without a comparison to reference values. Reference values are the values expected for a healthy person, typically expressed as an amount per volume. They are also sometimes called “normal” values.

How can I find out about your tests and learn more about what they mean?

Please contact QualeVita for more information. We can provide you summaries about the role each analyte in the human body, websites to visit and peer-reviewed scientific papers. We suggest that you start your reading by visiting three websites:

  • Agency for Toxic Substances and Disease Registry: atsdr.cdc.gov
  • Centers for Disease Control: cdc.gov
  • US Department of Health and Human Services: hhs.gov/programs/index.html# Then click on various titles (links) associated with Prevention and Wellness.
Who receives the QualeVita report?

You can specify who besides you and your doctor will receive a QualeVita report.

What will happen after I receive my test results?

Your doctor or health provider will review the results with you.  During this consultation,  further steps will be discussed.